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Distance and Travel Tips from Myrtle Beach to Biloxi, MS

Discover the distance from Myrtle Beach to Biloxi, Mississippi, travel options, driving routes, and tips for a smooth trip between these Gulf Coast destinations.

Distance and Travel Tips from Myrtle Beach to Biloxi, MS

Planning a trip from Myrtle Beach, South Carolina, to Biloxi, Mississippi? You might be wondering how far these two popular Gulf Coast cities are from each other and the best ways to travel between them. Whether you’re driving, flying, or considering other options, I’ll help you understand the distance, travel time, and tips to make your journey easier.

Both Myrtle Beach and Biloxi offer beautiful coastal experiences, but they are quite a distance apart. Knowing the exact mileage and travel routes can help you plan your trip better. Let’s explore the details, including driving routes, flight options, and what to expect along the way.

How Far Is Myrtle Beach to Biloxi, Mississippi?

The straight-line distance between Myrtle Beach, SC, and Biloxi, MS, is about 600 miles. However, the actual driving distance is longer because roads don’t run in a straight line. The most common driving route covers approximately 670 miles.

This distance means a road trip between the two cities usually takes around 10 to 11 hours, depending on traffic and stops. It’s a full day of driving, so planning breaks and overnight stays can make the trip more comfortable.

  • Driving distance: About 670 miles

  • Estimated driving time: 10 to 11 hours

  • Direct flight distance: Approximately 600 miles

Best Driving Routes from Myrtle Beach to Biloxi

When driving from Myrtle Beach to Biloxi, you have a few route options. The fastest and most common route uses major highways and interstates, making the trip smoother and easier to navigate.

Route 1: Via I-20 W and I-59 S (Fastest Route)

  • Start on US-17 S from Myrtle Beach

  • Merge onto I-20 W near Florence, SC

  • Continue on I-20 W toward Atlanta

  • Take I-59 S from Meridian, MS, toward Biloxi

  • Exit onto US-90 E to reach Biloxi

This route covers about 670 miles and takes roughly 10.5 hours. It passes through cities like Florence, SC; Augusta, GA; Atlanta, GA; and Meridian, MS.

Route 2: Via I-95 S and I-10 W (Scenic Coastal Option)

  • Take US-17 S from Myrtle Beach

  • Merge onto I-95 S toward Savannah, GA

  • Connect to I-16 W toward Macon, GA

  • Join I-75 S briefly, then I-10 W in Florida

  • Follow I-10 W to Biloxi, MS

This route is longer, about 720 miles, and can take 11 to 12 hours. It offers more coastal scenery and passes through Savannah, GA, and Tallahassee, FL.

Flight Options Between Myrtle Beach and Biloxi

If you prefer flying, you can find flights connecting Myrtle Beach International Airport (MYR) and Gulfport-Biloxi International Airport (GPT), which serves Biloxi. There are no direct flights, so you will have at least one stop, usually in Atlanta, Charlotte, or Dallas.

  • Flight duration: Around 4 to 6 hours total, including layovers

  • Airlines: American Airlines, Delta, and Southwest often operate connecting flights

  • Booking tips: Book early for better prices and check layover times carefully

Flying can save time compared to driving, but you’ll need to arrange transportation from the airport to your final destination in Biloxi.

Travel Tips for the Myrtle Beach to Biloxi Trip

Whether you drive or fly, here are some tips to make your trip smoother:

  • Plan your stops: If driving, schedule breaks every 2-3 hours to stretch and refresh.

  • Check traffic and weather: Use apps like Google Maps or Waze for real-time updates.

  • Book accommodations in advance: If you plan to stay overnight, cities like Atlanta or Meridian offer good hotel options.

  • Fuel up wisely: Gas stations are plentiful along interstates, but fill up before rural stretches.

  • Pack snacks and water: Especially for the long drive, to stay comfortable and hydrated.

What to See and Do Along the Way

The drive from Myrtle Beach to Biloxi passes through several interesting cities and attractions. You can break your trip into parts and explore some highlights:

  • Florence, SC: Historic downtown with shops and restaurants.

  • Augusta, GA: Home of the Masters Golf Tournament and riverwalk parks.

  • Atlanta, GA: Major city with museums, parks, and dining.

  • Meridian, MS: Small city with Civil War history and local museums.

  • Gulfport, MS: Near Biloxi, offering beaches, casinos, and seafood.

These stops can add interest and rest to your journey.

Where to Stay in Biloxi, Mississippi

Biloxi is known for its casinos, beaches, and seafood. When you arrive, you’ll find many hotel options to suit your needs and budget.

  • Beau Rivage Resort & Casino: Luxury hotel with a casino, spa, and fine dining.

  • Hard Rock Hotel & Casino Biloxi: Modern rooms, entertainment, and gaming.

  • IP Casino Resort Spa: Large resort with pools and restaurants.

  • Holiday Inn Express & Suites Biloxi Beach: Budget-friendly option near the beach.

  • Courtyard by Marriott Biloxi North/D'Iberville: Comfortable stay with easy highway access.

Booking early is recommended, especially during peak seasons or events.

How to Get Around Biloxi

Biloxi is a spread-out city, so having a car is the easiest way to explore. Here are your options:

  • Rental cars: Available at Gulfport-Biloxi International Airport and in town.

  • Taxis and rideshares: Uber and Lyft operate in Biloxi but may be limited in some areas.

  • Public transit: The Coast Transit Authority runs buses, but routes are limited.

Driving gives you the most freedom to visit casinos, beaches, and nearby towns like Ocean Springs.

Summary

The distance from Myrtle Beach to Biloxi is about 670 miles by road, taking roughly 10 to 11 hours to drive. Flying is faster but requires at least one connection. You can choose between the fastest interstate route or a more scenic coastal drive. Along the way, you’ll find interesting cities to visit and plenty of places to rest.

Biloxi offers many hotel options, from luxury resorts to budget stays. Renting a car is the best way to get around and enjoy all the city has to offer. With good planning, your trip between these two Gulf Coast destinations can be comfortable and enjoyable.

FAQs

How long does it take to drive from Myrtle Beach to Biloxi?

Driving from Myrtle Beach to Biloxi usually takes about 10 to 11 hours, covering roughly 670 miles via the fastest interstate route.

Are there direct flights between Myrtle Beach and Biloxi?

No, there are no direct flights. You will need to connect through airports like Atlanta, Charlotte, or Dallas, with total travel time around 4 to 6 hours.

What is the best route to drive from Myrtle Beach to Biloxi?

The fastest route is via I-20 West to I-59 South, passing through cities like Florence, Augusta, and Meridian.

What hotels are recommended in Biloxi?

Popular hotels include Beau Rivage Resort & Casino, Hard Rock Hotel & Casino, and IP Casino Resort Spa, offering a range of amenities and locations.

Is it better to rent a car in Biloxi?

Yes, renting a car is the easiest way to explore Biloxi and nearby areas, as public transit is limited and rideshares may not be available everywhere.

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